论文部分内容阅读
Objective: To detect the expressions of FEZ1 and Survivin in small cell lung cancer (SCLC) and poorly differenti-ated squamous cell carcinoma (PDSCC), and to approach a theoretical basis for clinical diagnosis and treatment. Methods: Immunohistochemical and flow cytometry method were used to detect the expressions of FEZ1 and Survivin. Apoptosis ratio and cell proliferation index in normal lung tissue, SCLC and PDSCC were analyzed. Results: The expressions of FEZ1 and Survivin were significantly different between SCLC and PDSCC (P < 0.05). The apoptosis ratio and proliferation index of normal lung tissue were lower than those of PDSCC and SCLC, with a significant difference (P < 0.05). Conclusion: The expressions of FEZ1 and Survivin are significantly different between SCLC and PDSCC, indicating that detecting the expres-sions of the two indexes may be helpful for clinical diagnosis.
Objective: To detect the expressions of FEZ1 and Survivin in small cell lung cancer (SCLC) and poorly differenti-ated squamous cell carcinoma (PDSCC), and to approach a theoretical basis for clinical diagnosis and treatment. Methods: Immunohistochemical and flow cytometry method were Results: The expressions of FEZ1 and Survivin were significantly different between SCLC and PDSCC (P <0.05). The apoptosis rate of FEZ1 and Survivin ratio and proliferation index of normal lung tissue were lower than those of PDSCC and SCLC, with a significant difference (P <0.05). Conclusion: The expressions of FEZ1 and Survivin are significantly different between SCLC and PDSCC, indicating that detecting the expres-sions of the two indexes may be helpful for clinical diagnosis.