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目的对比黄葵胶囊和贝那普利片治疗慢性肾炎患者的疗效,对比治疗后患者尿蛋白肌酐比值和尿NAG酶的变化。方法将本院2006年8月—2007年8月期间收治的100例慢性肾炎患者,随机分为研究组和对照组各50例。研究组给予黄葵胶囊治疗,对照组给予贝那普利片治疗,两个疗程后对两组患者的症状反应、尿蛋白肌酐比值(UP/Ucr)、尿NAG和肾功能的变化等各方面进行对比观察。结果经比较治疗组的治疗有效率(88.0%)高于对照组(86.0%),但差异无统计学意义(P>0.05)。两组患者的尿蛋白肌酐比值和尿NAG均有效降低,且肾功能得到改善。结论黄葵胶囊对慢性肾炎患者治疗效果较之于贝那普利片稍胜一筹,疗效较佳。
Objective To compare the efficacy of Huang Kui capsule and benazepril tablet in the treatment of patients with chronic nephritis and to compare the urinary protein creatinine ratio and urinary NAG enzyme after treatment. Methods One hundred patients with chronic nephritis treated in our hospital from August 2006 to August 2007 were randomly divided into study group (50 cases) and control group (50 cases). The study group was treated with Huang Kui capsule, while the control group was given benazepril tablets. The symptoms, urinary protein creatinine ratio (UP / Ucr), urinary NAG and renal function in two groups were compared after treatment Comparative observation. Results Compared with the control group (88.0%), the treatment effective rate of the treatment group was higher than that of the control group (86.0%), but the difference was not statistically significant (P> 0.05). Urine protein creatinine ratio and urinary NAG were effectively reduced in both groups, and renal function was improved. Conclusion Huang Kui capsule in patients with chronic nephritis treatment than benaopril tablets slightly better, better effect.