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目的通过检测急性脑梗死(ACI)患者在低频超声治疗仪治疗前后不同时段血浆D-二聚体的动态变化,研究经低频超声治疗后急性脑梗死与D-二聚体的相关性。方法将80例发病24h内入院治疗的急性脑梗死患者如组,随机分为治疗组和对照组各40例。二组患者均以二组患者均以神经内科治疗药物治疗,治疗组同时给予低频超声波治疗,应用双抗体夹心法及全自动生化分析仪测定两组病人治疗前后D-二聚体含量,评价入、出院时的临床神经功能缺损程度,观察其D-二聚体的变化和临床疗效的差别。结果治疗14d后,治疗组D-二聚体比较对照组下降更明显(P<0.01)治疗组总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论经颅低频超声治疗脑梗死的疗效与预后具有显著改善作用对。
Objective To investigate the dynamic changes of plasma D-dimer in patients with acute cerebral infarction (ACI) before and after low-frequency ultrasound treatment before and after treatment to study the relationship between acute cerebral infarction and D-dimer after low-frequency ultrasound treatment. Methods A total of 80 patients with acute cerebral infarction admitted to hospital within 24 hours of onset were randomly divided into treatment group (40 cases) and control group (40 cases). Two groups of patients were treated with neurology medicine in both groups. At the same time, the treatment group was given low-frequency ultrasound treatment. The content of D-dimer in both groups before and after treatment was measured by double antibody sandwich method and automatic biochemical analyzer , The clinical neurological deficit at discharge, observed the difference of its D-dimer and clinical efficacy. Results After treatment for 14 days, the D-dimer in the treatment group decreased more obviously than that in the control group (P <0.01). The total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). Conclusion Transcranial low-frequency ultrasound treatment of cerebral infarction efficacy and prognosis have a significant effect on the improvement.