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目的:探讨受卵体外受精-胚胎移植(IVF-ET)治疗结局和疗效。方法:回顾分析2004年9月至2005年11月在本中心接受卵子赠送IVF-ET的患者共21周期的临床资料。赠卵组(20例)均采用长方案控制性超排卵行IVF-ET。受卵组(21例)采用激素替代治疗准备子宫内膜。赠卵者所赠卵子与受卵者丈夫精液行IVF-ET。选择同期常规IVF-ET患者55例做对照。结果:赠卵组种植率和临床妊娠率(7.3%,15.79%)明显低于受卵组(34.9%,52.38%)和同期IVF-ET组(21.19%,34.55%),P<0.05。结论:受卵IVF-ET是治疗卵巢功能不良和遗传原因不能生育健康后代妇女的有效方法;激素替代周期的种植率和临床妊娠率高于控制性超排卵周期。
Objective: To investigate the outcome and efficacy of IVF-ET. Methods: The clinical data of 21 cycles of IVF-ET donated by eggs in our center from September 2004 to November 2005 were retrospectively analyzed. Eggs group (20 cases) were used long-term controlled ovulation IVF-ET. Ovum (21 cases) received hormone replacement therapy to prepare the endometrium. Ovum donated egg and her husband semen IVF-ET. Select the same period conventional IVF-ET patients with 55 cases as a control. Results: The implantation rate and clinical pregnancy rate in ovum group (7.3%, 15.79%) were significantly lower than those in ovariectomized group (34.9%, 52.38%) and IVF-ET group (21.19%, 34.55%, P <0.05). Conclusion: Ovovariate IVF-ET is an effective treatment for women with ovarian dysfunction and genetic causes that can not give birth to healthy offspring. The implantation rate and clinical pregnancy rate of hormone replacement cycle are higher than that of controlled ovarian hyperstimulation.