论文部分内容阅读
目的采用两种不同妊娠期糖尿病(gestational diabetes mellitus,GDM)诊断标准,分析其对GDM检出率及围产期母婴结局的影响。方法将2010年7月至2012年6月在遵义市妇幼保健院产检及住院分娩并采用教科书《妇产科学》(2008年第7版)诊断标准进行诊断的6 357例孕妇纳入老标准组,将2012年7月至2014年6月产检及住院分娩并采用新标准进行诊断的5 753例孕妇纳入新标准组。并对检出的GDM孕妇给予干预,观察两组的妊娠结局。结果新标准组检出GDM 263例(4.57%),高于老标准组165例(2.60%)(P<0.05);两组剖宫产率、新生儿窒息率(新标准组为57.79%、1.14%,老标准组为61.82%、1.82%)比较差异无统计学意义(P>0.05);新标准组妊娠期高血压疾病、巨大儿、羊水过多发生率分别为6.46%、5.70%、6.08%低于老标准组(分别为12.12%、10.91%、11.52%)(P<0.05)。结论按照新的诊断标准,虽检出率增加,但GDM所致围产不良结局有所降低,及早诊断,可及时干预,从而改善妊娠结局。
Objective To evaluate the effect of gestational diabetes mellitus (GDM) on the detection rate of GDM and the outcome of perinatal maternal and infant. Methods From June 2010 to June 2012, 6 357 pregnant women, who were diagnosed at childbirth and delivery hospital of Zunyi MCH and diagnosed according to the textbook Obstetrics and Gynecology (7th Edition, 2008), were included in the old standard group, 5 753 pregnant women who were diagnosed during childbirth and hospitalization from July 2012 to June 2014 with the new criteria were included in the new standard group. GDM pregnant women were given interventions to observe the pregnancy outcome in both groups. Results The new standard group detected 263 cases of GDM (4.57%), which was higher than the 165 cases (2.60%) of the old standard group (P <0.05). The cesarean section rate and neonatal asphyxia rate were 57.79% 1.14%, 61.82% in the old standard group and 1.82% in the old standard group, respectively) (P> 0.05). The incidences of hypertensive disorder complicating pregnancy, macrosomia and amniotic fluid in the new standard group were 6.46% and 5.70% 6.08% lower than the old standard group (12.12%, 10.91%, 11.52%, respectively) (P <0.05). Conclusion According to the new diagnostic criteria, although the detection rate increased, but the adverse outcomes caused by GDM decreased, early diagnosis and timely intervention to improve pregnancy outcomes.