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目的：回顾分析胸大肌肌皮瓣修复口腔缺损的并发症，明确并发症发生有关的因素，探讨减少其发生的措施。方法：对1990～1996年间所行168例应用带蒂胸大肌肌皮瓣修复口腔颌面部缺损的病人临床资料进行多元素回归分析。168例患者中，男性120例，女性48例，年龄26～79岁。结果：168例皮瓣中，25例出现不同程度坏死（14．9％）；22例发生瘘管（13．1％）；伤口感染39例（23．2％）。与并发症有关的因素有多种，并发症使住院日明显延长。结论：作者认为切取肌皮瓣时，应避免过偏远，中大面积缺损应配合邻近或游离皮瓣修复。
OBJECTIVE: To retrospectively analyze the complications of pectoralis major myocutaneous flap in repairing oral defects and to clarify the factors related to the occurrence of complications and to explore the measures to reduce its occurrence. Methods: The clinical data of 168 patients who underwent pedicled pectoralis major myocutaneous flap to repair oral and maxillofacial defects from 1990 to 1996 were analyzed by multivariate regression analysis. Of 168 patients, 120 were male and 48 were female, aged 26-79 years. Results: In 168 cases, 25 cases showed necrosis (14.9%), fistula occurred in 22 cases (13.1%) and wound infection in 39 cases (23.2%). And complications related to a variety of factors, complications, hospitalization was significantly longer. CONCLUSION: The authors believe that the removal of myocutaneous flap should be avoided too far, large defects in the area should be combined with the adjacent or free flap repair.