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通过对一组(28例)多发性骨髓瘤病人进行免疫分型及临床分析,发现本组病人发病年龄较国外低,都有不同程度的贫血,骨髓增生度减低占多数,高钙血症少;1例IgD多发性骨髓瘤在血清蛋白电泳图像上见较明显的M蛋白高峰,血清,总蛋白增高;本组病人免疫分型以IgG为主,占53%。建议对怀疑多发性骨髓瘤的病人,当用普通加热法检查尿BenceJones蛋白阴性时,应做血尿免疫电泳,以提高对多发性骨髓瘤的诊断率。
Through immunophenotyping and clinical analysis of a group of 28 patients with multiple myeloma, it was found that the age of onset in this group of patients was lower than that in other countries. They all had varying degrees of anemia, a decrease in the degree of myeloproliferative disease, and less hypercalcemia. 1 case of IgD multiple myeloma showed significant peak of M protein in serum protein electrophoresis image, serum and total protein increased; the immunophenotype of this group was mainly IgG, accounting for 53%. It is recommended that in patients with suspected multiple myeloma, when the normal urine test for urinary Bence Jones protein is negative, hematuria immunoelectrophoresis should be performed to improve the diagnostic rate of multiple myeloma.