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作者采用气相色谱－热能分析法，测定了７０份鼻咽癌患者和正常人尿样中的挥发性亚硝胺水平。两组尿样中的二甲基亚硝胺水平分别为０．５５±０．４０μｇ／Ｌ、０．４５±０．３４μｇ／Ｌ，两者比较无显著性差异（Ｐ＞０．０５）；二乙基亚硝胺水平分别为０．２２±０．２０μｇ／Ｌ、０．３２±０．２６μｇ／Ｌ，两者比较亦无显著性差异（Ｐ＞０．０５）。然而，鼻咽癌患者尿样中的亚硝胺阳性检出率高达６２．９％，正常人为５４．３％，提示鼻咽癌的发生与当地居民的饮食因素和内源性亚硝胺形成有关。
The authors used gas chromatography-thermal analysis to determine the levels of volatile nitrosamines in urine samples from 70 patients with nasopharyngeal carcinoma and normal controls. The dimethylnitrosamine levels in the urine samples of the two groups were 0.55±0.40 μg/L and 0.45±0.34 μg/L, respectively, and there was no significant difference between the two groups (P>0.05). The diethylnitrosamine levels were 0.22±0.20 μg/L and 0.32±0.26 μg/L, respectively, and there was no significant difference between the two groups (P>0.05). However, the positive rate of nitrosamines in urine samples from patients with nasopharyngeal carcinoma was as high as 62.9% and 54.3% in normal subjects, suggesting that the occurrence of nasopharyngeal carcinoma and dietary factors and endogenous nitrosamine formation in local residents. related.