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越来越多的证据表明,氧化应激在动脉粥样硬化(AS)性心血管疾病形成中的重要作用。最近的一些病理学方面的研究也发现,某些特异性的调节物参与了这些氧化应激反应并可促进AS斑块在血管壁的形成和破裂。这些特异性的调节物能在人体内测出并作为AS性心血管疾病风险评估的生物标记物,本文就这些生物标记物作一综述。
There is growing evidence that oxidative stress plays an important role in the development of atherosclerotic cardiovascular disease. Some recent pathological studies have also found that certain specific modulators are involved in these oxidative stress reactions and promote the formation and rupture of AS plaques in the blood vessel wall. These specific modulators can be measured in humans and serve as biomarkers for the risk assessment of AS-induced cardiovascular disease. These biomarkers are reviewed in this paper.