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登革病毒能否引起神经系统疾病目前仍有争议,为证实登革热在急性神经系统感染中的作用,作者在越南南方进行了一项前瞻性研究。对1995年中疑似中枢神经系统(CNS)感染的住院患者,用病毒培养、PCR及抗体测定等方法检测其血清和脑脊液(CSF)中的登革病毒。 流行病学:在378例(成人228例、儿童150例)疑似CNS感染者中有16例(成人9例、儿童7例)感染登革病毒,占4.2％。对照组为同期住院的286例患者,其中4例
Whether dengue virus can cause neurological diseases is still controversial. To confirm the role of dengue fever in acute neurological infections, the authors conducted a prospective study in southern Vietnam. Inpatients with suspected central nervous system (CNS) infection in 1995 were tested for dengue virus in serum and cerebrospinal fluid (CSF) using methods such as virus culture, PCR and antibody assays. Epidemiology: Of 378 (228 adults and 150 children) suspected CNS infections, 16 (9 adults and 7 children) were infected with dengue virus (4.2%). The control group was 286 patients hospitalized in the same period, of which 4 cases