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目的:分析奥曲肽、生长抑素治疗肝硬化上消化道出血的疗效。方法:选取我院收治的84例肝硬化上消化道出血患者,将其随机分为A组和B组,各42例。给予A组奥曲肽治疗,给予B组生长抑制素治疗,观察并比较两组临床疗效和随访期不良反应发生率。结果:A组临床有效率78.57%,低于B组的97.62%,差异比较有统计学意义(P<0.05);A组不良反应发生率11.90%,稍高于对照组的4.76%,比较差异无统计学意义(P>0.05)。结论:生长抑素治疗肝硬化上消化道出血的临床有效率较奥曲肽的高,值得应用于临床治疗。
Objective: To analyze the curative effect of octreotide and somatostatin on upper gastrointestinal hemorrhage of liver cirrhosis. Methods: Eighty-four patients with upper gastrointestinal hemorrhage who were admitted to our hospital were randomly divided into group A and group B, with 42 cases in each group. A group of patients given octreotide treatment, given Group B somatostatin treatment, observation and comparison of clinical efficacy and adverse reactions in the follow-up of the incidence. Results: The clinical effective rate in group A was 78.57%, which was lower than 97.62% in group B, the difference was statistically significant (P <0.05). The incidence of adverse reactions in group A was 11.90%, slightly higher than that in control group, 4.76% No statistical significance (P> 0.05). Conclusion: The clinical efficacy of somatostatin in the treatment of cirrhosis and upper gastrointestinal bleeding is higher than that of octreotide, which is worth to be used in clinical treatment.