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目的：回顾性分析３０ 例恶性肉芽肿放射治疗效果和与预后有关的因素。方法：自１９８１ 年１ 月～１９９１ 年１２ 月收治３０ 例恶性肉芽肿病人。全部患者采用６０ Ｃｏ 外照射， Ｄ Ｔ４０ ～７０ Ｇｙ／４ ～７ｗ 。１２ 例患者放疗前后服用环已亚硝脲１００ ～１２０ｍｇ 。结果：３ 年及５ 年生存率分别为６３ ．５ ％ （１９／３０） 和５３ ．２ ％（１６／３０） ，放疗剂量、病变侵及范围及有无持续发热是影响预后的重要因素。结论：放疗是恶性肉芽肿首选治疗方法，肿瘤量以５０ ～６０ Ｇｙ／５ ～６ｗ 为宜，化疗可改善症状但不提高远期生存率。
OBJECTIVE: To retrospectively analyze the radiotherapy effects and prognostic factors of 30 cases of malignant granuloma. Methods: Thirty patients with malignant granuloma were admitted from January 1981 to December 1991. All patients with 60 Co external irradiation, D T40 ~ 70 Gy / 4 ~ 7w. 12 patients before and after taking the ring has nitrosourea 100 ~ 120mg. Results: The 3-year and 5-year survival rates were 63. 5% (19/30) and 53. 2% (16/30), radiation dose, the extent of disease invasion and the presence or absence of persistent fever are important prognostic factors. Conclusion: Radiotherapy is the first choice of treatment of malignant granuloma. The optimal dose of tumor is 50-60 Gy / 5-6 w, chemotherapy can improve the symptoms but does not improve the long-term survival rate.