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目的:观察土茯苓熏洗方治疗湿热下注型外阴阴道假丝酵母菌病(VVC)的临床疗效。方法:将106例患者随机分为治疗组、对照组各53例,治疗组采用土茯苓熏洗方熏洗坐浴及达克宁栓治疗,对照组仅用达克宁栓治疗,共治疗7天。结果:治疗后及随访到治疗后第30天,治疗组愈显率分别为96.0%、96.0%,对照组分别为54.9%、56.9%,2组比较,差异均有统计学意义(P<0.05)。治疗后第1、4天,治疗组症状消失率为50.0%、82.0%,对照组分别为21.6%、35.3%,2组比较,差异均有统计学意义(P<0.05)。治疗7天,治疗组重度VVC患者皮损痊愈率为81.8%(9/11),对照组为45.5%(5/11),2组比较,差异有统计学意义(P<0.05)。治疗后治疗组以阳性杆菌为主、无菌丝和孢子的图片较对照组多(P<0.05)。结论:土茯苓熏洗方联合达克宁栓治疗湿热下注型VVC疗效确切,值得临床推广。
Objective: To observe the clinical efficacy of tuckahoe smoked washing prescriptions in treating damp-heat infusion type vulvovaginal candidiasis (VVC). Methods: 106 patients were randomly divided into treatment group and control group, with 53 cases in each group. The treatment group was treated with Smoked Bath of Smilax Smilax and Dacron Hydrochloride suppository, while the control group was treated with MDK alone for 7 days. Results: After treatment and on the 30th day after treatment, the cure rates in the treatment group were 96.0% and 96.0%, respectively, while those in the control group were 54.9% and 56.9% respectively. There was significant difference between the two groups (P <0.05 ). On the first and the fourth day after treatment, the rate of disappearance of symptoms in the treatment group was 50.0% and 82.0%, respectively, and 21.6% and 35.3% in the control group respectively. There was significant difference between the two groups (P <0.05). After 7 days of treatment, the cure rate of skin lesions in severe VVC patients was 81.8% (9/11) in the treatment group and 45.5% (5/11) in the control group. There was significant difference between the two groups (P <0.05). After treatment, positive bacilli were the main treatment group, and no more mycelium and spore pictures than the control group (P <0.05). Conclusion: The combination of Smoked Poria and Radix Moxibustion in treating damp-heat infusion of VVC is effective and worthy of clinical promotion.