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应用单克隆抗体碱性磷酸酶抗碱性磷酸酶桥联酶标法 ( APAAP)检测 1 69例小儿肺炎及毛细支气管炎鼻咽部脱落细胞病毒抗原——呼吸道合胞病毒 ( RSV)、流感病毒A、B亚型 ( Flu- A、Flu- B)、副流感病毒 1 .3及 2亚型 ( PIV1.3、PIV2 )、腺病毒 ( Adv)等 6种病毒抗原。结果 :阴性 77例 ,阳性 92例 ,阳性率 5 4 .44% ,两种及以上病毒感染 1 7例 ,占 1 8.47%。阳性病例中 RSV比例最大 ,共 42例 ,占病毒性肺炎及毛细支气管炎的 38.1 3% ,主要感染 6个月以下的小婴儿。通过对所检 6种病毒连续 4年的动态研究发现。RSV感染有较大幅度上升 ,而流感病毒 A、B亚型 ,腺病毒及副流感 2亚型感染则呈明显下降趋势。提示 :呼吸道合胞病毒是小儿下呼吸道感染的主要病原
One hundred and ninety-nine pediatric patients with pneumonia and bronchiolitis nasopharyngeal exfoliated cell virus antigen-respiratory syncytial virus (RSV) were detected by the monoclonal antibody alkaline phosphatase alkaline phosphatase-linked enzyme-linked immunosorbent assay (APAAP) A, B subtype (Flu-A, Flu-B), parainfluenza virus 1.3 subclass (PIV1.3, PIV2), adenovirus (Adv) and other 6 kinds of viral antigens. Results: 77 cases were negative, 92 cases were positive, the positive rate was 54.44%. Two or more viruses were infected, accounting for 1 8.47%. Among the positive cases, RSV accounted for the largest proportion, 42 cases, accounting for 38.1% of viral pneumonia and bronchiolitis, the main infection in infants less than 6 months old. Through the seizure of six kinds of viruses for four consecutive years of dynamic research found. RSV infection increased significantly, and influenza A, B subtype, adenovirus and parainfluenza 2 subtype infection showed a significant downward trend. Tip: Respiratory syncytial virus is the main pathogen of pediatric lower respiratory tract infection