论文部分内容阅读
目的观察急性心肌梗死患者血清半胱氨酸蛋白酶抑制剂C(CysC)水平的变化以及探讨其临床意义。方法选择急性心肌梗死患者50例,不稳定型心绞痛患者50例,另选经冠状动脉造影检查证实无冠状动脉病变者50例作为对照组。所有病例入院第2天清晨检测CysC水平。结果急性心肌梗死组CysC水平明显低于不稳定型心绞痛组及对照组,1周后明显升高与入院24h内的水平比较,差异有统计学意义(P<0.01)。结论血清CysC水平在一定程度上可作为急性心肌梗死早期诊断和估计预后的参考指标。
Objective To investigate the changes of serum cystatin C (CysC) in patients with acute myocardial infarction and to explore its clinical significance. Methods Fifty patients with acute myocardial infarction and 50 patients with unstable angina pectoris were enrolled in this study. Fifty patients with coronary artery lesions confirmed by coronary angiography were selected as the control group. All cases were admitted on the second day early detection of CysC levels. Results The level of CysC in acute myocardial infarction group was significantly lower than that in unstable angina pectoris group and control group. The level of CysC in the acute myocardial infarction group was significantly higher than that in the control group after one week, and the difference was statistically significant (P <0.01). Conclusion The serum CysC level can be used as a reference index for the early diagnosis and prognosis of acute myocardial infarction.