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磷地尔(fostedil)是一种新的钙桔抗剂,化学名为今(2一苯井喷吐基)等基膦酸二乙酪。现已表明,本并喀哇环以不同取代基取代后,并不增强磷地尔对离体豚鼠心脏冠状血管的舒张活性,但膦酸二乙酯部分则对活性起重要作用。作者研究了甲基膦酸二乙酯基直接引入到具有心血管作用
Phosphorus (fostedil) is a new calcium antagonist, the chemical name for the present (2-benzophenanyl) and other phosphonic acid two cheese. It has been shown that the substitution of different substituents on the Kadavan ring does not enhance the diastolic activity of phosphodiphos on the coronary vasoconstriction of isolated guinea pig hearts, whereas the diethyl phosphonate fraction plays an important role in the activity. The authors studied the direct introduction of diethyl methylphosphonate into a cardiovascular system