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Great progress has been made in the treatment of lung cancer,notably a diversification in therapeutic drugs including immunotherapies such as those based on PD-1.Among these,there are many anti-disease molecules extracted from Chinese traditional medicine,such as artemisinin and tanshinones.Tanshinones,including Tanshinone Ⅰ (T1),Tanshinone ⅡA (T2A),and cryptotanshinone (CT),are the liposoluble constituents of Salia miltiorrbiza,a traditional herb,which has favorable medicinal value.Of particular interest is the cytotoxic effect that tanshinone has on tumor cells,which is thought to occur primarily through the induction of apoptosis and interdiction of cell cycle progression,angiogenesis,cell invasion,and metastasis.Previous studies have indicated that the apoptosis-inducing effect of tanshinones might effectively target and inhibit the growth of human lung cancer cells [1].Thus,it is reasonable to speculate that tanshinones may play an important role in the treatment of non-small cell lung cancer (NSCLC).