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在不育症的诊断和治疗中,最关键的难题是缺少评价精子生育力的可靠方法。常规使用的精液分析有一定局限性,而评价精子功能的其它生物检测手段,包括去透明带仓鼠卵精子穿透试验也难以预测精子生育力。因此,需要寻找一种鉴别精子质量的细胞标志物,除用于不育症的诊断外,也可用来确定精子功能的缺陷。作者由生化途径研究了合成和转移能量的关键酶——精子肌酸激酶(CK)的活
The most critical challenge in the diagnosis and treatment of infertility is the lack of reliable methods of evaluating sperm fertility. Routine use of semen analysis has its own limitations, and other bioassays that evaluate sperm function, including the zona pellucida penetration test, are not predictive of sperm fertility. Therefore, there is a need to find a cell marker that identifies sperm quality and, in addition to the diagnosis of infertility, can also be used to determine sperm function deficiencies. The biochemical pathway by the author of the synthesis and transfer of energy key enzyme - sperm creatine kinase (CK) live