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目的:应用TCT(thinprep cytologic test)技术分析适龄女性宫颈疾病的患病情况,评价TCT技术的临床应用价值。方法:收集2010月12月～2011年11月该院10 539例女性的TCT检查结果,均按TBS分级系统标准做出诊断,对TCT发现上皮内瘤变且自愿作阴道镜活检的患者,将检查结果按年龄分为5组进行统计分析。结果:TCT检查结果与组织活检的符合率高,40～49岁组宫颈上皮内瘤变的患病率高于其他年龄组(P<0.05),29岁以下组患病率有增高趋势。结论:TCT是宫颈疾病监测的有效方法;宫颈疾病的高发年龄是40～49岁,并有年轻化趋势,应普及筛查。
OBJECTIVE: To analyze the prevalence of cervical diseases in women of same age using TCT (thinprep cytologic test) technique and evaluate the clinical value of TCT. Methods: The TCT results of 10 539 women in our hospital from December 2010 to November 2011 were collected. All patients were diagnosed according to the TBS grading system. For those patients who found intraepithelial neoplasia on TCT and voluntarily performed colposcopy biopsy, The test results were divided into 5 groups by age for statistical analysis. Results: The coincidence rate of TCT and tissue biopsy was high. The prevalence of cervical intraepithelial neoplasia in 40-49 age group was higher than that in other age groups (P <0.05). The prevalence of TCT in lower age group was increased. Conclusion: TCT is an effective method to monitor cervical diseases. The incidence of cervical diseases is 40-49 years old and tends to be young. Screening should be universal.