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热休克蛋白(HSP)是细胞在应激条件下产生的一类蛋白质,它与细胞的许多病理及生理过程密切相关,近年来研究表明HSP在中枢神经系统中并不是传统上认为的参与神经损伤,相反具有神经保护作用。热休克蛋白家族中几种主要的HSP都具有中枢神经保护作用,而每种HSP的保护作用都具有各自的特异性。由于HSP的中枢神经保护作用,其临床应用前景也成为人们关注的焦点。
Heat shock proteins (HSPs) are a class of proteins produced by cells under stress conditions. They are closely related to many pathological and physiological processes in cells. In recent years, studies have shown that HSPs are not traditionally thought to be involved in nerve damage in the central nervous system , On the contrary with neuroprotection. Several major HSPs in the heat shock protein family have central nervous system protection, and the protective effect of each HSP has its own specificity. Due to the central nervous protective effect of HSP, its clinical application prospect has also become the focus of attention.