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目的：探讨肝硬变、肝癌患者血清甲状腺激素水平及其临床意义。方法：采用放射免疫分析法对４５例肝硬变和２５例肝癌患者血清三碘甲腺原氨酸（Ｔ３）、甲状腺素（Ｔ４）、促甲状腺激素（ＴＳＨ）进行检测。结果：各研究组血清Ｔ３水平明显低于正常对照组（Ｐ＜０．０１）；肝硬变失代偿期低于代偿期（Ｐ＜０．０１），肝癌Ⅲ期低于肝癌Ⅰ、Ⅱ期（Ｐ＜０．０１）；肝硬变失代偿期和肝癌Ⅲ期患者血清Ｔ４也低于正常对照组（Ｐ＜０．０１和Ｐ＜０．０５）。结论：肝硬变、肝癌患者呈低Ｔ３血症，并且血清Ｔ３水平与肝脏的损害程度有一定关系。
Objective: To investigate the serum thyroid hormone level in patients with cirrhosis and liver cancer and its clinical significance. Methods: Serum triiodothyronine (T3), thyroxine (T4) and thyrotropin (TSH) in 45 patients with cirrhosis and 25 patients with hepatocellular carcinoma were detected by radioimmunoassay. Results: Serum T3 level in each study group was significantly lower than that in the normal control group (P <0.01); the decompensation stage of liver cirrhosis was lower than that in compensatory phase (P <0.01) (P <0.01). The serum T4 level of patients with decompensated liver cirrhosis and stage Ⅲ hepatocellular carcinoma was also lower than that of the normal control group (P <0.01 and P <0.05). Conclusion: Patients with liver cirrhosis and hepatocellular carcinoma have hypo-T3 hyperlipidemia, and the level of serum T3 is related to the extent of liver damage.