论文部分内容阅读
目的 研究 2 0例正常人99m锝—二乙基乙酰基替苯胺亚氨二醋酸 (99mTc -EHIDA)肝胆动态功能显像定量分析 ,以便建立本实验室的正常值 ,为胆道功能性疾病的诊断提供帮助。方法 静脉注射99mTc -EHIDA后 ,用Genesys单光子发射计算机断层扫描仪 (SPECT)进行肝胆动态显像。结果 肝脏泌胆分数 (HEF)为 1 0 0 % ,半排时间 (Tex)为 (2 0 .8±6 .3)min ,高峰时间 (Tup)为 (4.6± 2 .7)min。胆囊排胆分数 (GBEF)为 (56.9± 1 8.5) % ,排胆期 (GBEP)为 (1 5± 7.4)min,排胆率 (GBER) 4 .2 %。正常胆系泌胆时相分析 :肝、胆囊、胆总管、胆管口括约肌及十二指肠胆汁出现时间分别为 (2 .3± 0 .7)min、(1 1 .7± 3.4)min、(1 3.5±3 .3)min、(2 2 .7±6 .3)min和 (2 3.5±8.2 )min;高峰时间分别为 (1 0 .5±2 .5)min、(40 .1±7.8)min、(2 2 .7±8.6)min、(45 .3± 8.8)min和(46.2±7.4)min ,5名受检者重复检查结果 ,相关性好 (r=0 .96) ,两均数差异无显著性意义(P >0 .0 5)。结论 99mTc -EHIDA肝胆动态显像定量分析 ,方法可靠 ,重复性好 ,不但能对胆汁排泄动力学研究提供胆汁排泄路径中各部位的功能特点 ,而且可以动态显示整个路径的形态 ,为临床诊断疾病提供了无创伤的新技术
Objective To study the quantitative analysis of 99m Tc-diethylacetanilimine (99mTc -EHIDA) in hepatobiliary dynamic imaging in 20 normal subjects in order to establish the normal value of this laboratory and to diagnose the biliary tract functional diseases provide help. Methods 99mTc-EHIDA was injected intravenously into the liver and gallbladder with Genesys single photon emission computerized tomography (SPECT). Results The hepatic secretion score (HEF) was 100%, the median time (Tex) was (20.8 ± 6.3) min, and the peak time (TAMP) was (4.6 ± 2.7) min. The GBEP was 56.9 ± 1 8.5%, the GBEP was 1 5 ± 7.4 min and the GBER was 4.2%. Normal gallbladder urinary phase analysis: liver, gallbladder, common bile duct, biliary sphincter and duodenal bile were (2. 3 ± 0. 7) min, (1 1 .7 ± 3.4) min, (1 3.5 ± 3. 3) min, (2 2 .7 ± 6. 3) min and (2 3.5 ± 8.2) min, peak time were (1 0 .5 ± 2. The results of five patients’ repeated examination showed good correlation (r = 0.96), ± 7.8 min, (22.7 ± 8.6) min, (45.3 ± 8.8) min and (46.2 ± 7.4) , No significant difference between the two mean (P> 0.05). Conclusion Quantitative analysis of 99mTc -EHIDA dynamic imaging of liver and gallbladder is reliable and reproducible. It not only provides the functional characteristics of various parts of the bile excretion pathway in the study of bile excretion dynamics, but also can dynamically display the morphology of the entire path for the clinical diagnosis of disease Provides a new non-invasive technology