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众所周知,LHRH 能够刺激垂体前叶释放 LH和 FSH,LH 和 FSH 转而控制卵巢和睾丸的功能。一些实验表明通过主动免疫引起针对 LHRH 的免疫中和作用可抑制大鼠,绵羊和绒猴的卵巢功能。并且能抑制雄性动物的生殖功能。本文作者研究了LHRH 主动免疫短尾弥猴后对其月经周期、卵巢类固醇激素以及正反馈的影响。实验动物力体重8～11kg,月经周期正常(29.3±8天)的健康短尾弥猴8只。其中3只对照组仅给予破伤风类毒素和弗氏完全佐剂注射。5只实验
As we all know, LHRH can stimulate the anterior pituitary LH and FSH release, LH and FSH in turn control ovarian and testicular function. Some experiments show that the immune neutralization against LHRH caused by active immunization can inhibit ovarian function in rats, sheep and marmosets. And can inhibit male reproductive function. The authors studied the effect of LHRH on immunization of macaque monkeys on their menstrual cycles, ovarian steroid hormones, and positive feedback. Experimental animals weighing 8 ~ 11kg, normal menstrual cycle (29.3 ± 8 days) 8 healthy macaques. Three of the control groups were given only tetanus toxoid and Freund’s complete adjuvant injection. 5 experiments