前哨淋巴结活检目前是公认且广泛应用于乳腺癌和黑色素瘤的技术

• 作 者: Malcolm R Kell Michael J Kerin 赵卫红
• 机 构: senior specialist registrar,Breast Check Eccles Unit Department of Surgery, Mater Misericordiae,Hosp
• 出 处: 英国医学杂志(中文版)
• 发表日期: 2004年06期
• 关键词: 前哨淋巴结活检 腋窝淋巴结清扫 区域淋巴结 黑色素瘤 淋巴结群 肿瘤侵袭 淋巴结阴性 肿瘤外科 淋巴转移 外科医生

近10年来,前哨淋巴结活检已逐步成为评价恶性肿瘤病人区域淋巴结状况的微创技术,仅取出一小部分淋巴结就可以明确一个淋巴结群的状态。这些淋巴结位于区域淋巴结的前沿:如果恶性肿瘤侵袭区域淋巴结,必须首先经过前哨淋巴结。因此,若前哨淋巴结受侵,区域淋巴结中后面的淋巴结将可能受侵。与传统的腋窝淋巴结清扫相比,局限的前哨淋巴结活检更具特异性,并减少手术创伤和术后发病率。现在,前哨淋巴结活检已得到普遍应用,大部分肿瘤外科医生把它作为诊断步骤的一部分。

In the past 10 years, sentinel lymph node biopsy has gradually become a minimally invasive technique for evaluating the status of regional lymph nodes in patients with malignant tumors. Only a small number of lymph nodes can be removed to confirm the status of one lymph node group. These lymph nodes are located at the forefront of regional lymph nodes: If a malignant tumor attacks a regional lymph node, it must first pass through the sentinel lymph node. Therefore, if the sentinel lymph node is impacted, the lymph nodes in the regional lymph nodes may be invaded. In contrast to conventional axillary lymph node dissection, localized sentinel lymph node biopsy is more specific and reduces surgical trauma and postoperative morbidity. Sentinel lymph node biopsies are now widely used and are used by most oncology surgeons as part of a diagnostic procedure.