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目的:探讨儿童哮喘发作与呼吸道合胞病毒感染关系。方法:在我院选择儿童哮喘40例患儿设为哮喘组,另选择同时期40例健康儿童设为正常组,对所有儿童均进行血清呼吸道合胞病毒检测,并统计IgM与IgE及血清干扰素IFN-γ之间的关系。结果:哮喘组患儿呼吸道合胞病毒特异性抗体Ig G阳性率、IgM阳性率及总阳性率与正常组相比明显较高,P<0.05。近期感染过呼吸道合胞病毒患儿血清呼吸道合胞病毒IgM与血清IgE水平、IFN-γ水平呈相关性,P<0.05。结论:儿童哮喘发作与呼吸道合胞病毒感染存在相关性。
Objective: To investigate the relationship between childhood asthma attacks and respiratory syncytial virus infection. Methods: 40 children with asthma in our hospital were selected as the asthma group and 40 healthy children in the same period were selected as the normal group. Serum respiratory syncytial virus was detected in all children, and IgM, IgE and serum interference The relationship between IFN-γ. Results: The Ig G positive rate, IgM positive rate and total positive rate of respiratory syncytial virus-specific antibody in children with asthma were significantly higher than those in normal group (P <0.05). Serum IgE and IFN-γ levels of IgM in children with respiratory syncytial virus infection have a significant correlation (P <0.05). Conclusions: There is a correlation between childhood asthma attacks and respiratory syncytial virus infection.