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近年来有许多研究报告强调,在慢性肾功能衰竭(CRF)伴发甲状腺机能减退时,由于两者的临床表现有不少重叠之处,以致诊断发生困难。作者在8例近期内进行慢性持续性血液透析的CRF 患者对此作了研究,其中3例合并原发性甲状腺机能减退(A 组),5例甲状腺机能正常(B 组)。应用特异性免疫学方法检测血清甲状腺素和促甲状腺素(TSH)对促甲状腺素释放激素(TRH)的反应性,然后对两组加以比较。结果血清 TSH 在 A 组明显增高,B 组则均为正
In recent years, many studies emphasize the difficulty of diagnosis due to many clinical manifestations of CRF associated with hypothyroidism. The authors studied 8 patients with chronic persistent hemodialysis patients with CRF, 3 of whom had primary hypothyroidism (group A) and 5 had normal thyroid function (group B). Serum thyroxine and thyrotropin (TSH) responses to thyrotropin-releasing hormone (TRH) were measured by specific immunological methods and then compared between the two groups. Results Serum TSH was significantly increased in group A, while group B was positive