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用儿童白血病患者(包括急淋、急粒和慢粒)骨髓或外周血的白血病细胞提取DNA和RNA。以癌基因V-abl为探针,经Southern杂交实验发现了患者中原癌基因C-adl的扩增,还发现一个以前从
DNA and RNA are extracted from leukemic cells of bone marrow or peripheral blood of children with leukemia, including acute, acute and chronic granulocytes. Using the oncogene V-abl as a probe, Southern blotting revealed the amplification of the proto-oncogene C-adl in patients and found that a