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尖锐湿疣是由人乳头瘤病毒(HPV)感染而引起的性传播疾病(STD),其发病率近年来有明显增加趋势,现已居我国STD的第二位。主要由HPV6、11、16、18引起,HPV16、18感染可引起鳞状上皮异型增生,与肛门癌、外阴瘸、龟头癌的发生有一定关系,因此,及时诊断,选择合理有效的方法积极治疗尖锐湿疣是非常必要的。目前常用的治疗方法有:①化学腐蚀剂疗法如:足叶草酯(Podophgllin)、足叶草毒素(Podophyllotoxin)、三氯乙酸(Trchloroaceticacid)、二氯乙酸等,②表面化疗剂如5-氟尿嘧啶(5-FU);③物理疗法有冷冻、激光、电灼、微波、电离子治疗机等;④还可以手术治疗、干扰素等治疗方法。但这些单一治疗方法都不能根除人乳头瘤病毒(HPV),而只能去除外生性疣、改善症状和体征,容易复发。作者为探索新的治疗方法,自1992~1997年采用CO_2激光汽化、干扰素注射、5-FU外敷,病毒灵口服治疗患者105例,疗效满意,值得推广。
Genital warts is a sexually transmitted disease (STD) caused by human papillomavirus (HPV) infection. The incidence of genital warts has been increasing significantly in recent years and now ranks second in China. Mainly caused by HPV6,11,16,18, HPV16,18 infection can cause squamous dysplasia, and anal cancer, genital lame, glaucomatous cancer have a certain relationship, therefore, timely diagnosis, choose a reasonable and effective method of active treatment Condyloma acuminata is very necessary. Currently used treatments are: ① chemical etherification therapy such as: Podophgllin, Podophyllotoxin, trichloroacetic acid, dichloroacetic acid, etc .; ② surface chemotherapeutic agents such as 5 - fluorouracil ( 5-FU); ③ physical therapy with freezing, laser, electrocautery, microwave, iontophoresis machine; ④ also surgery, interferon and other treatment methods. However, none of these single treatments can eradicate human papillomavirus (HPV), and only remove exogenous warts, improve symptoms and signs, and easily recur. In order to explore new treatment methods, from 1992 to 1997, 105 patients were treated with CO2 laser vaporization, interferon injection, 5-FU topical, and Viral Ling oral. The results were satisfactory and worthy of promotion.