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卵巢是女性的重要生殖器官,具有维持机体内分泌系统的平衡、维持女性特征以及机体正常生理代谢的作用。药物对对卵巢功能的影响主要表现在:卵巢组织学改变、卵巢内分泌改变、卵巢早衰等方面。使用药物将对患者的卵巢功能产生不同程度的影响,影响的程度主要与药物的类型、组成、剂量以及患者的年龄等密切相关,卵巢功能的损害将严重影响患者的生活质量。本文主要从抗炎药物、抗肿瘤药物、抗排异药物和避孕药物四个药物种类对卵巢功能影响的研究进展进行综述。
Ovary is a female reproductive organs, with the maintenance of the body’s endocrine system balance, maintain the characteristics of women and the body’s normal physiological metabolism. The impact of drugs on ovarian function mainly in: ovarian histological changes, changes in ovarian endocrine, premature ovarian failure and so on. The use of drugs will have different degrees of ovarian function in patients with varying degrees of impact mainly on the type of drug, composition, dosage and the age of the patient is closely related to the damage of ovarian function will seriously affect the quality of life of patients. This article mainly reviews the research progress of ovarian function from four kinds of anti-inflammatory drugs, antineoplastic drugs, anti-rejection drugs and contraceptive drugs.