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目的：观察低密度脂蛋白－ 阿克拉霉素（ Ｌ Ｄ Ｌ Ａ Ｃ Ｍ） 复合物对小鼠肝癌 Ｈ２２ 细胞的细胞毒作用。方法： Ｍ Ｔ Ｔ 法及蛋白质合成抑制实验。结果： Ｍ Ｔ Ｔ 实验显示，与正常肝细胞组相比， Ｌ Ｄ Ｌ Ａ Ｃ Ｍ 复合物对 Ｈ２２ 细胞有更显著的生长抑制作用。蛋白质合成抑制实验除显示了 Ｌ Ｄ Ｌ Ａ Ｃ Ｍ 复合物的生长抑制作用外，还反映出该复合物作用的饱和性。结论： Ｌ Ｄ Ｌ Ａ Ｃ Ｍ 复合物对小鼠肝癌 Ｈ２２ 细胞有靶向杀伤作用。
OBJECTIVE: To observe the cytotoxicity of LDL-A C M complexes on mouse hepatoma H22 cells. Methods: M T T method and protein synthesis inhibition experiment. RESULTS: M T T experiments showed that the L D L A C M complex had a more pronounced inhibitory effect on H22 cells compared with the normal liver cell group. In addition to the inhibitory effect of the L D L A C M complex on protein synthesis inhibition experiments, the saturation of the complex was also reflected. Conclusion: L D L A C M complex has targeted killing effect on mouse hepatocellular carcinoma H22 cells.