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目的分析妊娠合并甲状腺功能减退与妊娠结局关系,同时观察临床治疗效果。方法选取来我院就诊148例妊娠合并甲状腺功能减退的孕妇,将其设定为观察组,而选取同一时间段甲状腺水平正常的孕妇134例,将其设定为对照组。分别观察两组孕妇在不同孕周生化检验促甲状腺激素、T3、T4水平。同时记录孕妇剖宫产与妊娠早期自然流产等情况。结果统计发现妊娠中期、晚期以及产后生化检验促甲状腺激素水平明显高于妊娠早期水平,相比差距显著(P<0.05)。妊娠中、晚期孕妇甲状腺水平控制情况明显高于对照组,相比差距显著(P<0.05),而产后甲状腺水平明显低于妊娠后期,相比差距显著(P<0.05),且观察组中足月儿生产率明显低于对照组,相比差距显著(P<0.05)。观察组孕妇妊娠早期流产率明显高于对照组,相比差距显著(P<0.05)。结论妊娠合并甲状腺功能减退孕妇应定期进行甲状腺水平监测,同时遵医嘱使用甲状腺激素药物,避免并发症发生。
Objective To analyze the relationship between pregnancy complicated with hypothyroidism and pregnancy outcome and to observe the effect of clinical treatment. Methods A total of 148 pregnant women with hypothyroidism undergoing pregnancy were enrolled in this study. They were selected as the observation group, while 134 pregnant women with normal thyroid gland at the same time were selected as the control group. The levels of thyroid-stimulating hormone, T3 and T4 in biochemical tests of two groups of pregnant women at different gestational weeks were observed respectively. Cesarean section at the same time recorded during pregnancy and spontaneous abortion and so on. Results Statistics showed that the thyroid-stimulating hormone levels in the middle, late and postpartum biochemical tests were significantly higher than those in early pregnancy (P <0.05). The control of thyroid level in the middle and late pregnant women was significantly higher than that in the control group (P <0.05), and the postpartum thyroid level was significantly lower than that in the late pregnancy (P <0.05) The monthly productivity was significantly lower than the control group, a significant difference (P <0.05). The abortion rate of pregnant women in observation group was significantly higher than that of control group in the first trimester of pregnancy (P <0.05). Conclusion Pregnant women with hypothyroidism should be regularly monitored thyroid levels, while prescribed thyroid hormone drugs, to avoid complications.