Many human tumors have activated the protein kinase Akt either by activation of the oncogene PI3Kα or by inactivation of the tumor suppressor PTEN.When act
Tumor development is thought to be the result of several oncogenic events.One long-standing hope in cancer research is that a common biochemical pathway for
How the programming and reprogramming of stern/progenitor cells regulate normal cell development and cancer is still not well known.One of the tools that we
Priming of naive tumor-specific CD8+ T cells can occur either through direct interaction with metastatic tumors in the tumor draining lymph nodes (TDLN), or
We have demonstrated that overexpression of Ha-rasval 12 oncogene induces autophagy in NIH3T3 cells.BNIP3 (Bcl-2/adenovirus E1B 19-kDa interacting protein 3