论文部分内容阅读
近来,钙拮抗剂被广泛应用于高血压病的治疗。硝吡乙甲醇是二氢嘧啶脱氢酶系的钙拮抗剂,具有对血管选择作用,抑制心肌作用弱,半衰期长,作用时间持久,服药方便等特点。作者对65例各类型(按WHO标准分类)高血压病进行了治疗观察。适应证:除了严重的肝肾功能障碍,药物过敏者,娠妇等门诊住院患者均可。服药方法:5～10mg,每日1次口服,疗程8周。效果:有效63.1%,有下降趋势者15.4%,无变化20%,无效1.5%。与患者性别,年龄,血压程度,有无合并症,治疗前用药与否等无关。副作用:较轻。占试验病例的7.1%。主要表现有颜面潮红的2例,心悸1例,头昏眼花1例,皮肤症状(湿疹,发红,搔痒)1例。作者认为硝吡乙甲醇作为钙拮抗剂可取代以往
Recently, calcium antagonists are widely used in the treatment of hypertension. Nifedipine is a dihydropyrimidine dehydrogenase system of calcium antagonists, with the role of the blood vessels, the role of myocardial inhibition of weak, long half-life, long duration of action, easy to take medication and so on. The author of 65 cases of various types (according to WHO standard classification) of hypertension were observed and treated. Indications: In addition to severe liver and kidney dysfunction, drug allergies, pregnant women and other outpatient inpatients can be. Medication Methods: 5 ~ 10mg, 1 day orally, course of treatment for 8 weeks. Effect: effective 63.1%, a downward trend of 15.4%, no change 20%, invalid 1.5%. And the patient’s gender, age, blood pressure, with or without complications, before treatment or not. Side effects: lighter. 7.1% of the trial cases. Mainly facial flushing in 2 cases, palpitations in 1 case, dizziness in 1 case, skin symptoms (eczema, redness, itching) in 1 case. The authors believe that nifedipine as a calcium antagonist can replace the past