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正常淋巴细胞的增殖和分化人体B细胞,通过各种细胞分裂素的组合而增殖,分化为产生抗体的细胞。在B细胞分化的初期,有原B细胞,也就是祖B细胞,该细胞是不能再形成免疫球蛋白的H链和L链遗传基因的原始细胞界限。白细胞介素-7(IL-7)和基质细胞干预这个祖B细胞,引起向原B细胞(pre-B)的分化和增殖,与此同时形成免疫球蛋白H链的遗传基因,于是在细胞浆中有了H链。IL-7作用于Pre-B细胞,引起Pre-B细
Normal lymphocytes proliferate and differentiate into human B cells, proliferate through the combination of various cytokines, and differentiate into antibody-producing cells. In the early stages of B cell differentiation, there are pro-B cells, that is, progenitor B cells, which are primitive cell boundaries that can no longer form the H chain and L chain genes of immunoglobulins. Interleukin-7 (IL-7) and stromal cells interfere with this progenitor B cell, causing the differentiation and proliferation of the pre-B cells, while forming the immunoglobulin H chain genes, so that in the cytoplasm In the H chain. IL-7 acts on Pre-B cells, causing Pre-B sperm