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本文采用微电泳方法观察到在大鼠丘脑腹内侧核（ＶＭ），微电泳给予乙酰胆碱（ＡＣＨ）使所有受试神经元自发放电频率加快，谷氨酸（ＧＬＵ）使大多数神经元放电加快，它们的作用依赖于电流强度；而γ氨基丁酸（ＧＡＢＡ）和氯苯氨丁酸则抑制大多数神经元的放电活动，但前者的作用快速而暂短，而后者的作用相对缓慢而持久。在微电泳ＡＣＨ或ＧＬＵ的过程中，给予ＧＡＢＡ可拮抗它们的兴奋作用。双钴碱使大多数神经元的自发放电频率加快，而阿托品和ＭＫ８０１对自发放电的影响较小。这些结果表明ＧＡＢＡ，ＡＣＨ和ＧＬＵ等递质活动在同一ＶＭ神经元有重要的会聚作用；ＧＡＢＡ对ＶＭ神经元有紧张性抑制作用。
Microelectrophoresis was used to observe the effects of acetylcholine (ACH) on the ventromedial nucleus (VM) of rat thallus. All the neurons were spontaneously discharged at a faster rate. Glutamic acid (GLU) accelerated the discharge of most neurons. Their effects depend on the intensity of the current; however, GABA and chlorbenzidine inhibit the firing activity of most neurons, but the effect of the former is fast and short, while the latter is relatively slow and long lasting . GABA can antagonize their excitatory effects during microelectrophoresis of ACH or GLU. Biclopidine accelerated the spontaneous firing of most neurons, while atropine and MK801 had less effect on spontaneous firing. These results indicate that the transmission activity of GABA, ACH and GLU have important convergent effect on the same VM neurons; GABA has an intense inhibitory effect on VM neurons.