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我院儿科自1992年开始,对入院的48例过敏性紫癜患儿,均应用西咪替丁与维生素C联合治疗,取得了满意疗效,现报告如下。1 临床资料男20例,女28例,50天至1岁以下9例,1岁至3岁12例,4至12岁27例。发病2～7天31例,7天以上17例。初发者39例,复发者9例。有诱因可查者28例,9例咽部及支气管感染,18例进食鱼、禽、蛋诱发,1例皮肤外伤后化脓性感染。48例均有皮肤紫癜,其中腹痛24例,大便带血20例,关节肿痛16例,肉眼及镜下血尿28例。36例混合型,12例单纯型。实验室检查:全部病人血红蛋白、血小板及出凝血时间均在正常范围。本组病人在应用西咪替丁及维生素C治疗前,28例用过一般抗组织胺药物和激素等治疗,疗效欠佳,改用此疗法。
Pediatrics in our hospital since 1992, the admission of 48 patients with Henoch-Schonlein purpura are cimetidine and vitamin C combination therapy, and achieved satisfactory results, are as follows. 1 clinical data of 20 males and 28 females, 50 days to 1 year old in 9 cases, 1 to 3 years in 12 cases, 4 to 12 years in 27 cases. The incidence of 2 to 7 days in 31 cases, more than 7 days in 17 cases. 39 cases of initial onset, recurrence in 9 cases. Incentives were found in 28 cases, 9 cases of pharynx and bronchial infection, 18 cases of fish, birds, eggs induced, 1 case of post-traumatic purulent infection. All 48 cases had purpura, including 24 cases of abdominal pain, 20 cases of bloody stool, 16 cases of joint swelling and pain, and 28 cases of macroscopic and microscopic hematuria. 36 cases of mixed type, 12 cases of simple type. Laboratory tests: All patients with hemoglobin, platelets and clotting time are in the normal range. The group of patients before the application of cimetidine and vitamin C treatment, 28 cases of general antihistamine and hormone therapy, poor efficacy, switch to this therapy.