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目的了解福建省疑似预防接种异常反应分布特征并评价福建省疑似预防接种异常反应监测系统。方法通过中国免疫规划监测信息管理系统和儿童预防接种信息管理系统,收集福建省2008-2011年监测个案数据,导出为EXCEL文件并采用描述性分析方法对AEFI分布特征和相关指标进行流行病学分析。结果福建省2008-2011年共报告AEFI个案2 574例,在AEFI分类诊断中,一般反应占78.24%;异常反应占16.31%。2008-2011年AEFI报告估算发生率为0.49/10万剂~7.23/10万剂。监测系统个案完整率为100%,及时报告率为85.86%。在所有报告病例中需调查的有1 210例,调查率为100%,48 h内调查数为1 174例,及时调查率为97.02%。结论福建省AEFI监测系统各项指标逐年提高,但仍有部分指标未达到国家要求,应加强培训和督导工作以提高监测质量。
Objective To investigate the distribution of anomalous response to suspected vaccination in Fujian Province and to evaluate the surveillance system of suspected anaphylaxis in Fujian Province. Methods The data of monitoring cases in Fujian Province from 2008 to 2011 were collected through the China Immunization Program Monitoring Information Management System and the Children’s Vaccination Information Management System. The data were exported to EXCEL file and the descriptive analysis method was used to carry out epidemiological analysis on the distribution characteristics of AEFI and related indicators . Results A total of 2 574 cases of AEFI were reported in Fujian province from 2008 to 2011. The average reaction rate was 78.24% in AEFI classification and 16.31% in abnormal reaction. The 2008-2011 AEFI report estimated the incidence to be 0.49 / 100,000 doses to 7.23 / 100,000 doses. The integrity of surveillance system cases was 100%, timely reporting rate was 85.86%. In all reported cases, 1,210 cases were investigated, the investigation rate was 100%, the number of investigations within 1 484 h was 1,174 and the prompt investigation rate was 97.02%. Conclusion The indicators of AEFI monitoring system in Fujian Province have been increasing year by year. However, some indicators still fail to meet the national requirements. Training and supervision should be strengthened to improve monitoring quality.