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目的探讨甲氨蝶呤配伍米非司酮联合治疗宫颈妊娠的效果。方法对1996年1月～2005年12月笔者所在医院收治的10例宫颈妊娠患者,肌注甲氨蝶呤20 mg每天1次,连用5 d,同时口服米非司酮50 mg,每天2次,5天为一疗程,治疗1～3疗程,8例患者用甲氨蝶呤50 mg宫颈局部注射1次。结果甲氨蝶呤联合米非司酮治疗宫颈妊娠10例均成功。结论甲氨蝶呤联合米非司酮治疗宫颈妊娠是可行的。
Objective To investigate the effect of methotrexate combined with mifepristone in the treatment of cervical pregnancy. Methods Ten patients with cervical pregnancy admitted to our hospital from January 1996 to December 2005 were treated with intramuscular methotrexate 20 mg once daily for 5 days and oral mifepristone 50 mg twice daily , 5 days for a course of treatment of 1 to 3 courses of treatment, 8 patients with methotrexate 50 mg cervical injection 1 time. Results Methotrexate combined with mifepristone treatment of cervical pregnancy in 10 cases were successful. Conclusion Methotrexate combined with mifepristone is feasible for cervical pregnancy.