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在一些伴有黄斑水肿的视网膜色素变性(RP)病人,使用醋氮酰胺(acetazolamide,一种碳酸酐酶抑制剂)后能有效地增进视力。然而,这种视功能改善与黄斑水肿减轻之间的关系由于治疗周期短而不能确定。本文报告7例RP病人的长期治疗效果。本组病例中,男4例,女3例,均为散发病例,其中5例荧光血管造影有黄斑水肿。ERG:3例记录不到,2例杆体/锥体RP型,2例锥体/杆体RP型。这些病人均接受视力矫正、视野、荧光血管造影、暗视和明视ERG
In some retinitis pigmentosa (RP) patients with macular edema, acetazolamide (a carbonic anhydrase inhibitor) is effective in improving vision. However, the relationship between this improvement in visual function and the reduction of macular edema is uncertain due to the short treatment period. This article reports the long-term treatment of 7 patients with RP. In this group of patients, 4 males and 3 females were sporadic cases, of which 5 cases of fluorescein angiography macular edema. ERG: 3 cases did not record, 2 cases of rod / cone RP, 2 cases of cone / rod RP. All of these patients underwent vision correction, visual field, fluorescein angiography, ophthalmoscopy and photopic ERG