Silica-bonded N-propyl sulfamic acid as an efficient recyclable catalyst for the synthesis of 3,4-di

• 作 者: Srinivasa Rao Jetti Anjna Bhatewara Tanuja Kadre Shubha Jain
• 机 构: Laboratory of Heterocycles,School of Studies in Chemistry & Biochemistry,Vikram University,
• 出 处: Chinese Chemical Letters
• 发表日期: 2014年03期
• 关键词: propyl heterogeneous aldehydes purification facile isolation aromatic friendly c

Silica-bonded N-propyl sulfamic acid(SBNPSA) catalyzed one-pot three component Biginelli condensation of different substituted aromatic aldehydes with ethyl acetoacetate and urea/thoiurea to the respective 3,4-dihydropyrimidin-2-(1H)-ones and thiones in environment friendly procedure is described. The facile reaction conditions, simple isolation and purification procedures of this method make it a good option for the synthesis of dihydropyrimidinones.

Silica-bonded N-propyl sulfamic acid (SBNPSA) catalyzed one-pot three component Biginelli condensation of different substituted aromatic aldehydes with ethyl acetoacetate and urea / thiuurea to the respective 3,4-dihydropyrimidin-2- (1H) -ones and thiones in The facile reaction conditions, simple isolation and purification procedures of this method make it a good option for the synthesis of dihydropyrimidinones.