论文部分内容阅读
本文对经各项神经耳科学检查诊断为椎-基底动脉供血不足的20例中枢性眩晕患者使用ibudilast(kekas)治疗的效果进行分析。其中男8例,女12例,年龄41～83岁,平均67.8岁。用药方法:本品30mg,分三次单独给与,半数病例根据需要同时给予调节植物神经药物、ATP或镇静剂1～3种。结果,给药后2周内症状消失者5例(占25％),4周以内消失者3例,6周以内3例,8周以上1例,到12周时除1例外,症状均得到改善。4例曾用其他药物治疗无效,改用本品后好转。所有伴随眩晕症状出现的眼震均恢复。Ibudilast是具有扩张血管平滑肌的药物,动物实验证实其增加脑血流量作用比罂
In this paper, the efficacy of ibudilast (kekas) treatment in 20 patients with central vertigo diagnosed with neurosurgical examination of vertebrobasilar insufficiency was analyzed. Including 8 males and 12 females, aged 41 to 83 years, mean 67.8 years old. Medication: The product 30mg, administered separately in three, half of the cases according to the need to give simultaneous regulation of autonomic drugs, ATP or sedatives 1 to 3 kinds. As a result, 5 patients (25%) disappeared within 2 weeks after administration, 3 patients disappeared within 4 weeks, 3 patients within 6 weeks, 1 patient more than 8 weeks, except 1 patient at 12 weeks, the symptoms were obtained improve. 4 cases had been treated with other drugs ineffective, switch to this product improved. All nystagmus with vertigo symptoms recovered. Ibudilast is a drug with dilation of vascular smooth muscle, animal experiments confirmed its role in increasing cerebral blood flow than papaya