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脑脊液(CSF)常规化验和细菌学检查是确诊细菌性脑膜炎的主要手段,然而在实际工作中还存在一些问题;(1)CSF沉渣涂片染色检出细菌的阳性率较低,而培养则需时较长;(2)若在腰穿前已用过抗菌素,其CSF的细菌性脑膜炎的特点常发生变化,且细菌分离常变为阴性;(3)部分病例的CSF改变可极不典型,例如美国某儿童医院十年统计结果揭示,约10%培养阳性的急性细菌性脑膜炎患儿入院时CSF细胞计数增
Cerebrospinal fluid (CSF) routine examination and bacteriological examination are the main means to diagnose bacterial meningitis. However, there are still some problems in practical work. (1) The positive rate of bacteria detected by CSF sediment smear is low, while the culture (2) If the antibiotics have been used before the lumbar puncture, the bacterial meningitis characteristics of CSF often change, and the bacteria often become negative; (3) CSF changes in some cases may be extremely Typical, for example, a decade of hospital statistics in the United States revealed that in about 10% of children with acute-positive bacterial meningitis, CSF counts increased