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作者对根除ＨＰ的三联疗法经典方案进行改良，减少其中四环素及甲硝唑的剂量及疗程，初步观察了该疗法的临床疗效。共３９例十二指肠溃疡患者接受低剂量三联疗法及对照ＣＢＳ治疗，其中ＨＰ根除率和溃疡治愈率分别为：８５．７％（１８／２１）对５．５％（１／１８），Ｐ＜０．００５；９５．２％（２０／２１）对６６．７％（１２／１８），Ｐ＜０．０５。溃疡１年复发率在ＨＰ根除者为５．３％（１／１９），未根除者为５３．９％（７／ １３），Ｐ＜０．０１。结果表明低剂量三联疗法具有较满意的临床疗效，副作用轻，病人易于耐受等优点，值得临床推广应用。
The author of the triple therapy eradicating HP classic program to improve and reduce the dose of tetracycline and metronidazole and medication, the initial observation of the clinical efficacy of the therapy. A total of 39 cases of duodenal ulcer patients underwent low-dose triple therapy and control CBS treatment, of which HP eradication rate and ulcer cure rates were: 85.7% (18/21) to 5.5% (1/18), P <0.005; 95.2% (20/21) vs 66.7% (12/18), P <0.05. The 1-year recurrence rate of ulcer was 5.3% (1/19) in eradication and 53.9% (7/13) in non-eradication, P <0.01. The results showed that low-dose triple therapy has more satisfactory clinical efficacy, side effects of light, easy to tolerate patients and so on, worthy of clinical application.