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患者,女,65岁。因反复咳嗽、咳痰35年,气急7年,加重1月,腹痛、腹泻粘冻样便20天入院。既往有精神病史,无癫痫史。体检:神清,口唇轻度紫绀。颈静脉轻度充盈。桶状胸,两肺呼吸音低,闻及散在湿罗音。心率100次/分,P_2>A_2。肝肋下1.5cm,质Ⅱ°。下肢轻度水肿。血象:WBC8.4×10~9/L,N 0.80。大便常规:脓细胞+,红细胞+,吞噬细胞找到。诊断:慢性肺心病伴感染,心衰Ⅱ°,菌痢。入院后用先锋霉素V号4g,联合0.2%诺氟沙星200ml静滴。第2天用药结束后2h,病人突然意识丧失,四肢抽搐,约2分钟后自行缓解。第3、4天用药后均有癫痫发作,每次发作均在静注药物后1~2h,考虑到诺氟沙星对中枢神经的副作用,立即停
Patient, female, 65 years old. Due to repeated coughing, phlegm for 35 years, seven years of agitation, aggravating January, abdominal pain, diarrhea, sticky samples were admitted to hospital for 20 days. Past history of mental illness, no history of epilepsy. Physical examination: God clear lips mild cyanosis. Jugular vein mild filling. Barrel chest, lungs breath sounds low, smell and scattered in the wet rales. Heart rate 100 beats / min, P_2> A_2. Liver ribs 1.5cm, quality Ⅱ °. Lower extremity mild edema. Blood: WBC8.4 × 10 ~ 9 / L, N 0.80. Stool routine: pus +, red blood cells +, phagocytic cells found. Diagnosis: Chronic pulmonary heart disease with infection, heart failure Ⅱ °, bacillary dysentery. Admitted with Vanguard ADM No. V 4g, combined with 0.2% norfloxacin 200ml intravenous infusion. 2 days after the end of medication 2h, the patient suddenly lost consciousness, limbs convulsions, about 2 minutes after the self-remission. 3,4 days after treatment have seizures, each attack are intravenous drugs 1 ~ 2h, taking into account the side effects of norfloxacin on the central nervous system, immediately stop