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目的探讨彩色多普勒超声在原发性肝癌患者放疗后的的应用价值。方法随访2008年10月~2010年6月某院收治的36例行三维适形放疗的原发性肝癌患者,在治疗前后均实施彩色多普勒超声检查方法 ,观察血流动力学变化。结果放疗前后彩色多普勒超声血流动力学检查项目包括周边收缩期峰值流速(cm/s)、周边舒张期最低流速(cm/s)、周边阻力指数、周边门脉样流速(cm/s)、内部收缩期峰值流速(cm/s)、内部舒张期最低流速(cm/s)、内部阻力指数、内部门脉样流速(cm/s),其中周边收缩期峰值流速(cm/s)、周边舒张期最低流速(cm/s)、内部收缩期峰值流速(cm/s)、内部舒张期最低流速(cm/s)放疗后显著低于放疗前(P﹤0.05),而周边阻力指数、周边门脉样流速(cm/s)、内部阻力指数、内部门脉样流速(cm/s)放疗前后差异无统计学意义(P﹥0.05)。结论彩色多普勒超声具有操作简单、无创的优点,应用于行三维适形放疗的原发性肝癌患者的疗效评估,诊断价值高,值得临床上推广应用。
Objective To explore the value of color Doppler ultrasound in patients with primary liver cancer after radiotherapy. METHODS: Thirty-six patients with primary liver cancer underwent three-dimensional conformal radiotherapy from October 2008 to June 2010 in our hospital. Color Doppler ultrasound was performed before and after treatment to observe the hemodynamic changes. Results The color Doppler ultrasonography hemodynamics before and after radiotherapy included peripheral peak systolic velocity (cm / s), peripheral diastolic minimum velocity (cm / s), peripheral resistance index, peripheral portal venous flow rate , Internal peak systolic velocity (cm / s), internal diastolic minimum velocity (cm / s), internal resistance index, internal portal venous flow rate (cm / s) (Cm / s), internal peak systolic velocity (cm / s) and internal diastolic minimum velocity (cm / s) after radiotherapy were significantly lower than those before radiotherapy (P <0.05) , Peripheral portal venous flow rate (cm / s), internal resistance index, internal portal venous flow rate (cm / s) before and after radiotherapy had no significant difference (P> 0.05). Conclusions Color Doppler ultrasound has the advantages of simple operation and non-invasive. It can be used in the evaluation of the curative effect of patients with primary liver cancer undergoing three-dimensional conformal radiotherapy. It is worth to be clinically popularized and applied.