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用ＨＲＰ逆行标记结合ＧＡＢＡ免疫组织化学染色法，在电镜下观察大鼠运动皮层胼胝体起源细胞的超微结构特征及其与ＧＡＢＡ能终末的关系。结果表明：大鼠运动皮层内的轴突终末与胼胝体起源细胞胞体仅形成对称型突触，与近端树突梗也形成少量的对称型突触，而与其树突棘则形成非对称型突触。与胞体和近端树突形成对称型突触的轴突终末主要是ＧＡＢＡ能终末。由这些ＧＡＢＡ能终末形成的轴－体突触数量占胞体表面总对称性突触数的８５．６４％（Ⅱ～Ⅲ层）和８２．１１％（Ⅴ～Ⅳ层）；近端树突上ＧＡＢＡ能终末所形成的突触占其表面总对称型突触数的７８．１３％（Ⅱ～Ⅲ层）和８４．７９％（Ⅴ～Ⅵ层）。这一结果提示，联系大鼠两侧运动皮层胼胝体起源细胞的抑制性传入，主要由ＧＡＢＡ能递质来调控。
Using HRP retrograde labeling combined with GABA immunohistochemical staining, the ultrastructural characteristics of the corpus callosum-derived cells in the motor cortex and their relationship with GABAergic terminals were observed under electron microscope. The results showed that the terminal axon in the motor cortex formed only symmetrical synapses with the cell bodies of the cells of the corpus callosum, and a small amount of symmetrical synapses with the proximal dendritic stem, while the dendritic spines formed asymmetric Synapse. Axonal terminals that form symmetrical synapses with cell bodies and proximal dendrites are predominantly GABAergic terminals. The number of axonal-synaptic terminals formed by these GABA terminals accounted for 85.64% (Ⅱ ~ Ⅲ) and 82.11% (Ⅴ ~ Ⅳ) of the total symmetry of the synaptic body surface. The number of proximal dendrites The synapses formed on the terminal of GABA accounted for 78.13% (Ⅱ ~ Ⅲ) and 84.79% (Ⅴ ~ Ⅵ) of the total number of symmetrical surface synapses. This result suggests that the inhibitory afferent cells of the corpus callosum cells associated with the motor cortex on both sides of the rat are mainly regulated by GABAergic neurotransmitter.