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为探讨气道炎症的非创伤性监测方法，采用酶联免疫法和荧光酶标法对１５例哮喘和１５例慢性阻塞性肺病（ＣＯＰＤ）患者痰液中白细胞介素（ＩＬ）－５和嗜酸细胞阳离子蛋白（ＥＣＰ）浓度进行检测。结果表明，哮喘患者痰液ＩＬ－５和ＥＣＰ浓度较ＣＯＰＤ患者明显增高，且哮喘患者痰液ＩＬ－５和ＥＣＰ浓度呈显著正相关。提示痰液分析有可能为气道炎症提供有效的非创伤性监测方法
In order to explore a noninvasive monitoring method of airway inflammation, the levels of interleukin (IL) -5 and phlegm in sputum of 15 patients with asthma and 15 patients with chronic obstructive pulmonary disease (COPD) were detected by enzyme-linked immunosorbent assay (ELISA) Acid cell cationic protein (ECP) concentration was detected. The results showed that asthma patients sputum IL-5 and ECP concentrations were significantly higher than COPD patients, and asthma sputum IL-5 and ECP concentrations were significantly correlated. Suggesting that sputum analysis may provide an effective non-invasive method of monitoring airway inflammation