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目的探讨血塞通联合硫辛酸在治疗2型糖尿病周围神经病变(DPN)中的应用及疗效。方法 48例2型糖尿病周围神经病变患者,按照随机原则将其分为对照组和观察组,各24例,两组患者入院后进行神经病变评分检测,其中对照组患者给予硫辛酸进行治疗,同时进行降糖、调脂、抗血小板等综合治疗;观察组患者在对照组治疗基础上给予血塞通进行治疗,治疗后对两组患者进行神经病变(TCSS)评分评定,对比治疗前后的变化情况。结果从TCSS评分统计结果来看,对照组治疗总有效率为79.2%;观察组治疗总有效率为91.7%,两组间对比差异有统计学意义(P<0.05)。结论在2型糖尿病周围神经病变患者的临床治疗过程中,采用血塞通联合硫辛酸进行治疗可显著改善患者病变症状,TCSS评分降低,预后情况良好,值得在临床上进行推广和应用。
Objective To investigate the application of Xuesaitong combined with lipoic acid in the treatment of type 2 diabetic peripheral neuropathy (DPN) and its curative effect. Methods Forty-eight patients with type 2 diabetic peripheral neuropathy were divided into control group and observation group according to the principle of randomness. Each group was divided into control group and observation group, and 24 patients in each group were tested for neuropathy score. Patients in control group were treated with lipoic acid, meanwhile, The patients in the observation group were treated with Xuesaitong on the basis of the treatment of the control group, and the neurological changes (TCSS) scores of the two groups were evaluated after the treatment, and the changes before and after the treatment were compared . Results According to the statistics results of TCSS, the total effective rate of the control group was 79.2%. The total effective rate of the observation group was 91.7%. The difference between the two groups was statistically significant (P <0.05). Conclusion In the course of clinical treatment of patients with type 2 diabetic peripheral neuropathy, Xuesaitong combined with lipoic acid can significantly improve the patient’s symptoms, reduce the TCSS score, the prognosis is good, it is worth in the clinical promotion and application.