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目的探讨自身免疫性溶血性贫血(AIHA)的血型血清学特性及输血疗效。方法对9例AIHA患者正、反定不一致、交叉配血不合的血清进行吸收、放散实验,鉴定血型和不规则抗体特异性。结果 9例确诊为AIHA患者,DAT分型以Ig G+C3为主。结论 AIHA患者在排除同种抗体干扰的情况下,采用配合性输注少白红细胞或同型洗涤红细胞,输后24 h平均血红蛋白(Hb)较输前上升5~12 g/L。
Objective To investigate the blood group serological characteristics and transfusion efficacy of autoimmune hemolytic anemia (AIHA). Methods 9 cases of AIHA patients with positive and negative reversed inconsistent cross-incompatible serum absorb, discharge experiment to identify the blood group and irregular antibody specificity. Results 9 cases were diagnosed as AIHA patients, DAT typing Ig G + C3-based. CONCLUSIONS: With the elimination of alloantibodies in AIHA patients, the mean Hb was increased by 5 ~ 12 g / L at 24 h after transfusion compared with the less transfused white or erythrocytes.