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目的观察慢性阻塞性肺疾病(简称慢阻肺)急性加重期应用无创正压通气治疗的临床效果。方法 56例慢性阻塞性肺疾病急性加重期患者随机分为观察组与对照组,各28例。对照组患者采用常规治疗,观察组患者在对照组基础上增加无创正压通气治疗,观察两组患者治疗前后动脉血二氧化碳分压(Pa CO2)、动脉血氧分压(Pa O2)、p H指标变化情况及两组使用抗生素时间和住院时间。结果治疗后观察组患者Pa CO2、Pa O2、p H指标改善明显,且使用抗生素时间和患者住院时间也明显低于对照组,两组数据差异均有统计学意义(P<0.05)。结论在慢性阻塞性肺疾病急性加重患者常规治疗上增加无创正压通气治疗效果更明显,能显著改善患者动脉血气各项指标,缩短使用抗生素时间和住院时间,促进患者快速康复。
Objective To observe the clinical effect of noninvasive positive pressure ventilation in acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Fifty-six patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into observation group and control group, with 28 cases in each group. The patients in the control group were treated with conventional therapy. The patients in the observation group were treated with noninvasive positive pressure ventilation on the basis of the control group. Pa CO2, Pa O2, p O2 Indicators of changes and the use of antibiotic time and hospital stay in both groups. Results After treatment, the PaCO 2, Pa O 2 and p H indexes in the observation group were significantly improved, and the antibiotic time and hospital stay were also significantly lower than those in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusion The treatment of patients with acute exacerbation of chronic obstructive pulmonary disease by noninvasive positive pressure ventilation is more effective in treating patients with acute exacerbation of chronic obstructive pulmonary disease. It can significantly improve the indexes of arterial blood gas, shorten the use of antibiotics and hospital stay, and promote the rapid recovery of patients.